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Cannabidiol, commonly called CBD, holds the promise of relieving a long list of ailments, from pain to epilepsy to multiple sclerosis. While this chemical compound comes from marijuana or its close relative hemp, CBD does not get users high, unlike another compound from the marijuana plant, tetrahydrocannabinol, or THC. But because the federal government classifies marijuana as an illegal drug and hemp has a complicated legal status, CBD is also highly controversial.
Thousands of CBD products—oils, tinctures, vaporization liquids, pills—are now widely available in stores and online. The World Anti-Doping Agency removed CBD from its list of banned substances in January, and some athletes now turn to it for pain relief instead of ibuprofen and related drugs. Researchers from major educational institutions, including Johns Hopkins and the University of California at San Diego, are studying its potential uses.
Some are even examining whether CBD might help in treating opioid addiction. Meanwhile, 47 states, plus Puerto Rico and Washington, D. See our interactive guide, below. As a result, consumers are left to navigate a confusing marketplace with little guidance about whether the products work, are safe, or even contain the ingredients manufacturers claim. Two recent events highlighted those issues, offering clarity on some—but not all—questions.
Early last week, the Food and Drug Administration for the first time approved a prescription drug made from marijuana, with CBD as its active ingredient. Called Epidiolex, the drug cut seizures by about 40 percent in people with two rare but devastating forms of epilepsy. It also includes language that could help clarify the uncertain legal status of CBD that comes from hemp. But whether that will translate into making CBD, at least from hemp, legal across the country is still unknown, says Collen Keahey Lanier, executive director of the Hemp Industries Association, a nonprofit trade group.
And while the hemp provision appears to have broad support, many Democrats and some Republicans object to other portions of the bill, which could jeopardize its passage. So, is there potential for CBD to treat disease and improve health?
Yes, just look at Epidiolex, says Donald Abrams, M. But in many other cases the claims are ahead of the science, Abrams says. Cannabidiol comes from one of two related forms of the cannabis plant: But the chemical structure is the same, regardless of the source, say medical and industry experts, so its effect on the body should be the same, too.
But CBD is often sold and used on its own. Importantly, hemp oil—found in soaps, cosmetics, and other products—is not the same as CBD oil. Hemp oil comes primarily from seeds of the plant, and the seeds contain only very small amounts of CBD, says Lanier at the Hemp Industries Association.
So hemp oil and other products made from the plant, such as rope and fabric, have no or only trace amounts of both CBD and THC. But hemp cultivation in the U. One goal of the new Farm Bill is to loosen those restrictions. And a growing body of preliminary research suggests that CBD has properties that could translate into better health. For example, CBD seems to be an anti-inflammatory, which in theory could help with arthritis and some forms of pain. And it has many effects on brain chemistry, which could ease anxiety and depression, among others.
Results from these studies, using doses of between and milligrams of CBD, indicate increases in brain activity in the left parahippocampal gyrus and decreases in the left amygdala-hippocampus complex, along with attenuated responses during the recognition of fearful facial expressions in the amygdala and the anterior cingulate. Interestingly, a case report was published by Shannon S et al. This case describes the gradual decrease in anxiety as measured by HAM-A: Hamilton Anxiety Rating Scale and feelings of stress and irritability from the marijuana non-use, while maintaining normal sleep quality.
According to the authors, the use of hemp-derived CBD oil helped in transitioning this patient away from habitual marijuana use while avoiding negative stress responses. The neuronal circuits within the brain that control many of these behaviors and emotions appear to be positively modulated by CBD. Given the ongoing, emerging human clinical data supporting the use of a hemp-derived CBD-rich extracts for modulating fear, anxiety and a healthy stress response, it looks like good old George Washington was a bona fide hemp pioneer.
This is from my personal experience, once you get those balanced your anxiety will diminish, then you can use the CBD cause your adrenal will need help, cause stress is a every day thing, so it will help with the anxiety! A lot of people are there for anxiety, so if you end up being allergic or something, you could probably get some ideas of where to turn to next.
Painting is a huge part of my recovery from hard drugs and to be honest I was scared to try this but with the THC removed I am able to paint and in other areas my life has changed like no depression , no feelings of being over whelmed….
Fred, thank you for your review. I am also a member of NA and AA and was worried about taking this product. Topical lotions, rubbed onto the skin, vary from person to person—some may feel it right away, others not for several hours. On the other hand, CBD in food products is likely to take longer—30 minutes or more—to be absorbed into your system. Read more about the pros and cons of each form. This is important mainly if you want to avoid the head-high that comes with THC, something that is important to many people who are considering CBD.
But knowing the THC level can be important for other reasons, too, including how effective a product might be, as well as where you can buy it. To be sure, that notion is more theoretical than proven. And only a small amount of THC—as low as the 0. So if you want a product that probably has a little THC but not so much to get you high, look for one made from hemp. Such products have the added benefit of being widely available, including online and in retail stores.
Maine and Vermont have legalized marijuana for recreational use but have yet to open recreational dispensaries. They may even sell buds or flower from marijuana strains that have been bred to have very low levels of THC, says Michael Backes, author of "Cannabis Pharmacy: Still, Lee cautions that some people are much more sensitive to the psychoactive effects of THC than others. So if you want to avoid the head-high, it's better to stick with CBD from hemp.
Many CBD products sold online and in retail stores come from hemp, not marijuana. And the source of that hemp can be important. Most hemp used in CBD products sold in the U. Among those sources, Lanier considers Colorado to have the most robust hemp program.
Note that the Farm Bill, now in Congress, may make it easier for farmers to grow hemp and expand the number of states where it is grown and tested. Products made with hemp grown overseas can be even more problematic, because they are not subject to any state or federal testing, say both Lanier and Boyar.
So for CBD products from hemp, check labels to see whether they say where it was grown, and look especially for those from Colorado. Not all products, however, include that information.
So in a dispensary or a retail store, ask the staff whether they know where the hemp was grown. And for products purchased online, check the companies' website to see whether it has that information, or contact the seller to ask the same question.
That document shows how a product performed on tests checking for CBD and THC levels, and the presence of contaminants. So any COA for those final products comes from testing the company arranged on its own. Though not all manufacturers take that step, many do, Lanier says. One state, Indiana, has made it easier for consumers to find these COAs. That suggests the lab adheres to high scientific standards.
What is CBD? What to know now about this cannabis product
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